Toxicology

Toxicology is one of the key subjects in the registration process. The team of highly skilled toxicologists at RIFCON is qualified in the assessment of short-term and acute effects, genotoxicity, carcinogenicity, reproductive toxicity as well as endocrine disrupting properties.

We monitor toxicological studies and prepare summaries. We also carry out QSAR assessments, profiling and read-across for relevance of impurities and metabolites. For product registration, we conduct exposure assessments and consider country-specific estimates of operator, worker, bystander and resident exposure. Our experts are knowledgeable on the specific demands associated with the regulatory framework as well as with country-specific aspects required for the assessment of toxicity and human risk. We prepare dossiers in compliance with current EU legislation for the registration of plant protection products and active substances. We also provide our clients with expert statements, authority replies, study evaluation and completeness checks.

Our Services

Toxicity

Acute and short-term / Reproductive toxicity / Genotoxicity / Cancerogenicity

Endocrine disrupting properties

Regulations (EU) No 528/2012 and (EC) No 1107/2009

In silico analysis

QSAR assessment / Profiling / Read-across

Exposure assessment

Operator/Worker/Bystander

Dossier preparation

Human toxicology

Study monitoring

Lab communication / Quotation inquiry / Monitoring services

Data analysis

Data gap analysis / CoC and GD compliance / Preliminary assessment / Cost estimation

Toxicity

Acute and short-term / Reproductive toxicity / Genotoxicity / Cancerogenicity

Endocrine disrupting properties

Regulations (EU) No 528/2012 and (EC) No 1107/2009

In silico analysis

QSAR assessment / Profiling / Read-across

Exposure assessment

Operator/Worker/Bystander

Dossier preparation

Human toxicology

Study monitoring

Lab communication / Quotation inquiry / Monitoring services

Data analysis

Data gap analysis / CoC and GD compliance / Preliminary assessment / Cost estimation